Psychiatry
For psychiatric practices managing insomnia alongside other conditions: a non-sedating option with objective evidence of increased deep and REM sleep, for patients where sedative burden is a concern.
Why sleep architecture matters
Most sleep aids are judged on onset and continuity. Defined Sleep's trial measured the objectively recorded proportion of deep (slow-wave) and REM sleep. In the FDA-registered Phase 2 crossover trial, participants with severe insomnia experienced increased deep and REM sleep and decreased light sleep, measured nightly by validated wearable actigraphy.
Use cases in psychiatric practice
- Psychiatric patients with comorbid insomnia where sedative burden is a concern
- Patients who decline or wish to discontinue prescription hypnotics
- Patients who want to avoid THC: Defined Sleep contains 0.0% THC, verified by third-party testing of every lot
“Insomnia is a common symptom associated with many psychiatric conditions, including anxiety. I recommend Defined Sleep to my psychiatry patients because it is a safe and effective alternative to stronger sleep medicines.”

“As a practitioner focused on cognitive health, Defined Sleep is the first supplement I've seen with rigorous clinical backing for actual sleep architecture improvements.”

Bring clinically validated restorative sleep to your patients
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Register as an HCP Ask our science & medical teamPublished study (JCSM) · ClinicalTrials.gov NCT05233761 · Ask our science & medical team
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.