Practice Areas

Psychiatry

For psychiatric practices managing insomnia alongside other conditions: a non-sedating option with objective evidence of increased deep and REM sleep, for patients where sedative burden is a concern.

Why sleep architecture matters

Most sleep aids are judged on onset and continuity. Defined Sleep's trial measured the objectively recorded proportion of deep (slow-wave) and REM sleep. In the FDA-registered Phase 2 crossover trial, participants with severe insomnia experienced increased deep and REM sleep and decreased light sleep, measured nightly by validated wearable actigraphy.

Use cases in psychiatric practice

  • Psychiatric patients with comorbid insomnia where sedative burden is a concern
  • Patients who decline or wish to discontinue prescription hypnotics
  • Patients who want to avoid THC: Defined Sleep contains 0.0% THC, verified by third-party testing of every lot

“Insomnia is a common symptom associated with many psychiatric conditions, including anxiety. I recommend Defined Sleep to my psychiatry patients because it is a safe and effective alternative to stronger sleep medicines.”

Dr. Nick Nissen
Nick Nissen, M.D.
Board-Certified Psychiatrist · CBT-I trained · Former Harvard Medical School faculty

“As a practitioner focused on cognitive health, Defined Sleep is the first supplement I've seen with rigorous clinical backing for actual sleep architecture improvements.”

Dr. Nick Nissen
Nick Nissen, M.D.
Board-Certified Psychiatrist · Former Harvard Medical School faculty

Review the trial data Combining with CBT-I

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