Clinical Use

Dosing & administration

Simple, consistent, and aligned with good sleep practice.

Defined Sleep sachet

Recommended dosing

  • Standard dose: 300 mg (two softgels) with water, one hour before going to bed.
  • Higher doses: up to 600 mg are well tolerated and may be more effective for some patients with extreme insomnia.
  • Consistency matters: sleep improves as a pattern, not in a single night. Encourage nightly use and evaluation over three to four weeks.

Administration counseling points

  • No alcohol or caffeine for at least three hours before bed — both interfere with efficacy (alcohol suppresses REM sleep)
  • Bed is for sleep: no TV, devices, or reading
  • Non-sedating: patients should expect gradual, natural drowsiness rather than being “knocked out”

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