Extensive clinical expertise is foundational to everything we do. Defined Sleep's founder, Science Advisory Board (SAB), and Medical Advisory Board (MAB) provide us with unparalleled guidance in providing integrity and transparency to consumers and healthcare providers.

Founder / CEO / CSO

Paul Muchowski, Ph.D. 

  • Ph.D. Biological Structure University of Washington

  • Post-doctoral training Max Planck Institute for Biochemistry

  • Professor University of Washington and University of California San Francisco

  • Neuroscience drug discovery (Soteria Therapeutics and Teva Pharmaceuticals)

  • Chair Emeritus of the Scientific Advisory Committee for the National Cannabis Industry Association

  • Published >60 highly cited research studies

  • Holds numerous patents

Science Advisory Board

Nephi Stella, Ph.D.

  • Professor University of Washington

  • Thought leader in cannabinoid science (>60 cannabinoid publications)

  • Discovered second endogenous cannabinoid (2-AG)

  • Founder: Stella Therapeutics

David Housman, Ph.D.

  • Professor Massachusetts Institute of Technology
  • Founder: Genzyme Genetics (Sanofi), Integrated Genetics, Variagenics, Somatix Therapy Corp.
  • Member, National Academy of Sciences and Institute of Medicine

Anne Young, M.D./Ph.D.

  • Professor Emeritus Harvard / Massachusetts General Hospital
  • Chair Emeritus, Harvard Neurology
  • Former President, Society for Neuroscience & American Neurological Association
  • Member, Institute of Medicine

John Clark, Ph.D.

  • Professor University of Washington
  • Founder: Oculon
  • Former President, Association for Research in Vision and Ophthalmology
  • Thought leader in aging on the eye

Medical Advisory Board

Elise Grenier, M.D.

Owner/Medical Director of Office MD and the G Spa in San Francisco

  • B.A. Integrative Biology University of California Berkeley
  • M.S. Molecular Biology and Biochemistry University of California, Berkeley
  • M.D. Finch University of Health Sciences/The Chicago Medical School
  • Internship/Residency University of California, San Francisco in Family Medicine at San Francisco General Hospital
  • Board Certified American Board of Family Medicine (ABFM) and American Academy of Aesthetics Medicine (AAAM)

Karen Muchowski, M.D.
Physician Palomar Health Medical Group

  • B.S. Physiology University of California Davis, Summa Cum Laude
  • M.D. University of California Davis
  • Internship/Residency Oregon Health Sciences University Family Medicine
  • Board Certified American Board of Family Medicine (ABFM)