Recommended by Sleep Physicians

OFFER EXPIRED

NTI 2026 5-Night Trial Offer for $5

JCSM Published

  • 125 trial participants

  • Up to 2x deep + REM sleep

  • NCT05233761

The only sleep supplement clinically proven to increase deep and REM sleep. Peer-reviewed. FDA-registered.

JCSM Published

  • 125 trial participants

  • Up to 2x deep + REM sleep

  • NCT05233761

OFFER EXPIRED
Recommended by Sleep Physicians
OFFER EXPIRED

The only sleep supplement clinically proven to increase deep and REM sleep. Peer-reviewed. FDA-registered.

JCSM Published

  • 125 trial participants

  • Up to 2x deep + REM sleep

  • NCT05233761

Promotional offers cannot be combined. Free or discounted trial purchases are ineligible for the money-back guarantee. Offer valid while supplies last.

Three Sleep Physicians

One Clinically Tested Product

"I recommend Defined Sleep to my patients with insomnia because it is highly effective, backed by a clinical trial, and safer than most OTC sleep aids."
Thuan Dang, MD, MPH
  • Board-certified Neurologist
  • American Board of Psychiatry and Neurology / Sleep Medicine
"As a practitioner focused on cognitive health, Defined Sleep is the first supplement I've seen with rigorous clinical backing for actual sleep architecture improvements."
Nick Nissen, MD
  • Board-certified Psychiatrist
  • Diplomate of the American Board of Psychiatry and Neurology
"I recommend Defined Sleep to post-menopausal patients; it is highly beneficial."
Elise Grenier, MD
  • Board-certified Family Practice Physician
  • American Board of Family Medicine

Why Defined Sleep

Up to 2× More Deep and REM Sleep, Clinically Proven

Proven Efficacy
Defined Sleep was shown to increase deep & REM sleep (restorative sleep) in a landmark human clinical trial.
Non-Sedating
Defined Sleep does not make you drowsy. It works by increasing deep & REM sleep. It contains no sedatives that ‘knock you out’.
Safe to Take Every Night
Defined Sleep is non-intoxicating, has no fall risk, and is non-addictive/not habit forming.


Optimal for Shift Workers
Study participants who slept during the day (e.g. shift-workers), were highly responsive to the treatment with Defined Sleep.
No Side-Effects
Defined Sleep displayed an excellent safety profile in our clinical trial, had no effect on heart rate or heart rate variability, and no adverse events were observed by study participants.
Drug-Test Safe
Our plant-based formula contains no THC or other ingredients screened for in workplace drug tests.



© Defined Research, Inc.